Fluoroquinolone poisoning is caused by antibiotics. It can result in grave side effects like nausea vomiting, diarrhea, muscle pain, depression, and psychosis. Floxing is a different name for this type of condition.
Patients who have suffered side effects of an antibiotic that contains fluoroquinolone/quinolone must stay away from fluoroquinolones. People suffering from kidney disease as well as those who’ve had an organ donation must be taken into consideration.
Nearly all quinolone antibiotics used are fluoroquinolones that contain a fluorine atom in their chemical structure and are effective against Gram-negative and Gram-positive bacteria.
Fluoroquinolones “kill bacteria by blocking enzymes that normally unravel DNA during cell replication. The majority of the time, these enzymes break DNA’s double helixand pass another part of the string through the gap and then mend the cut.
However, quinolones are able to bind to enzymes and prevent their repair. In the 1980s, researchers added fluorine atoms to the structure of the quinolones. This allowed antibiotics to penetrate every tissue in the body and even the central nerve system. It also increased their effectiveness against a vast spectrum of bacterial infections.
Fluoroquinolones may be useful for certain ailments which include life-threatening ones, where alternative antibiotics are not effective enough.
However, fluoroquinolones are overused just like other antibiotics. They have been linked to adverse side effects that have been reported over the years. The FDA has issued numerous warnings on their use. A number of label changes have been mandated as well as some fluoroquinolones come with black-box warnings.
What antibiotics are called fluoroquinolones?
These medications include the drugs ciprofloxacin (Cipro), gemifloxacin (Factive), the levofloxacin (Levaquin), moxifloxacin (Avelox) Norfloxacin (Noroxin) and ofloxacin (Floxin).
What is fluoroquinolone-related toxicity syndrome?
Signs + Symptoms
Some of the side effects of fluoroquinolone medicines have been proven to be potentially dangerous permanent, irreversible, and permanent. They include toxicity to the cardiovascular and central nervous systems, the musculoskeletal system, and central nervous system. Ciprotoxicity symptoms include:
– Damage to mitochondria and DNA
– Brain fog
– Peripheral Neuropathy
– Blurry Vision
– DNA Damage
– Depression/anxiety due to Gaba, Gut Damage and the result
– Tendonitis
– Muscle Atrophy
– Reflexes are more acute now.
Ciprotoxicity signs include low back pain and tendonitis, an arthralgia and tendon rupture. Fluoroquinolones may increase the chance of developing peripheral neuropathy by 47% in time.
Ciprofloxacin is shown to inhibit normal maintenance and transcription of mitochondrial DNA through altering the topology of mitochondrial DNA. Tendinitis, tendon rupture and other tendon injuries could result from the damage caused by mitochondria to tenocytes following fluoroquinolone treatment. It can also cause inflammation or fatigue.
For more information, click fluoroquinolone toxicity treatment
